Immunology
New drug tackles transplant complicationsNew drug tackles transplant complications

To reduce the number of discards and thus make more kidneys available, researchers and medical scientists from the European consortium MABSOT have created a new drug called OPN-305 to reduce inflammation of the donor organ after transplantation.

September 2014
Mary Reilly – fast-tracking rare disease drug candidates’ approvalMary Reilly – fast-tracking rare disease drug candidates’ approval

Giving drug candidates a special orphan status gives pharmaceutical companies incentives to bring them to patients

September 2014
New treatment against transplantation complications testedNew treatment against transplantation complications tested

A class of biotechnology drugs called monoclonal antibodies is now being tested in clinical studies to treat an unmet medical need post-transplantation, called delayed graft function

September 2014
Fighting resistance to antimalarial drugFighting resistance to antimalarial drug

Next-generation antimalarial drugs are much needed to address resistance issues to current treatments. New strategies may work by interfering with the biology of the parasite causing the disease. 

June 2014
Gordon Langsley – Focus on biological signalling to defeat malariaGordon Langsley – Focus on biological signalling to defeat malaria

The use of so-called kinases enzymes regulating several stages of the life cycle of the parasite causing malaria, offers new hopes for prevention and treatment of the disease. 

June 2014
On the track of the deadly parasite LeishmaniaOn the track of the deadly parasite Leishmania

Leishmaniasis is one of the most underreported and insufficiently monitored diseases in the world. According to the WHO more than 300.000 people are infected annually with the most severe form of this disease - kala-azar. The treatment against this forgotten disease becomes increasingly difficult, and sometimes impossible as the parasites developed resistance against the existing drugs. Now scientists from Europe, India and Nepal have joined forces within the European Research Project Kaladrug-R to regain control against this disease and develop new effective clinical tools.  

May 2014
Parasite surveillance to support policy against drug resistanceParasite surveillance to support policy against drug resistance

Surveillance tools can detect the incidence of different genetic varieties of the leishmaniasis parasite. And this enables development of local drug policies to better fight resistance.

May 2014
Jean-Claude Dujardin – Overcoming Leishmania’s drug-resistant Trojan horse effectJean-Claude Dujardin – Overcoming Leishmania’s drug-resistant Trojan horse effect

Leishmania parasites hijack macrophages turning them against their human hosts. New insights reveal how novel therapies can reverse this effect despite the parasite’s complex resistance.

May 2014
Mum’s diet mirrors child’s food allergiesMum’s diet mirrors child’s food allergies

A long-term study evaluating maternal diet’s impact on food allergy in later life is expected to uncover causes of allergy in children

April 2014
The fight against hepatitis C in EgyptThe fight against hepatitis C in Egypt

New ways to differentiate between chronic and self-clearing infections may help towards effective patient management and reduce drug costs. But there are major challenges in implementation.

April 2014
Matthew Albert - Egypt needs a hepatitis C vaccine urgentlyMatthew Albert - Egypt needs a hepatitis C vaccine urgently

Egypt faces a hepatitis C epidemic and existing drug costs are prohibitive. But new biomarkers may allow better patient management, lower costs and open a path towards a much-needed vaccine.

April 2014
Camille Locht – an innovative solution to infant whooping coughCamille Locht – an innovative solution to infant whooping cough

A new nasal live vaccine could be the solution for infants, whose immune system is not mature enough to effectively respond to traditional vaccines

January 2014
New Vaccine to Protect Babies from Whooping CoughNew Vaccine to Protect Babies from Whooping Cough

Whooping cough, also known as pertussis, is a bacterial infection that can be fatal. Now, a new nasal vaccination aimed at infants aims to address an unmet medical need against this disease 

January 2014
Nasal vaccine: towards an alternative to injection for infantsNasal vaccine: towards an alternative to injection for infants

Delivering a whooping cough and bronchiolitis vaccine through a single inhalation could become an alternative to traditional injections. However, such approach still requires fine tuning.

January 2014
Does Too Much Hygiene Cause Diabetes?Does Too Much Hygiene Cause Diabetes?

Scientists in northern Europe are conducting a major survey to determine whether standards of hygiene contribute to the development of auto-immune diseases such as type 1 diabetes  

January 2014
Kids can be too cleanKids can be too clean

Scientists are studying the potential link between lack of exposure to bugs in childhood and later development of allergies or diseases such as type 1 diabetes

January 2014
Vallo Tillman: the hygiene hypothesis is not yet a theoryVallo Tillman: the hygiene hypothesis is not yet a theory

A new study in Northern Europe is specifically designed to verify whether children need be in contact with pathogens in their early years to help them develop a strong immune system

January 2014
A HIV vaccine preventing healthy cells’ infectionA HIV vaccine preventing healthy cells’ infection

Scientists are testing a new HIV vaccine candidate aiming at blocking the virus from entering the body, but it is still early days

November 2013
Nicolas Mouz - progressing towards an efficient HIV vaccineNicolas Mouz - progressing towards an efficient HIV vaccine

A new AIDS vaccine designed to inhibit the entrance of the HIV virus into the cells is in first stage clinical trials in humans

November 2013
New Hopes for an AIDS VaccineNew Hopes for an AIDS Vaccine

December 1st is the annual World AIDS Day, a perfect opportunity to look at how medical research is progressing to fight the disease. 

November 2013
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