France, Genetics, Health
Twins help progress and diagnosis of rare Myasthenia
Fourteen pairs of identical twins joined the EU funded medical project “ Fight-MG ”, to fight Myasthenia Gravis . This rare autoimmune disease leads to abnormal fatigability of various skeletal muscles.
Sonia Aknin-Berrih: How rare models suggest new treatment strategies
Myasthenia Gravis (MG) is a rare auto-immune disease—whereby patients’ immune systems attack their own bodies— arising from a breakdown in communications between the nervous and muscular systems.
Network of experts join forces to fight rare disease
Collaboration between research groups is key in tackling rare diseases such as auto-immune disease Myasthenia Gravis (MG). Indeed, the rarity of the disease means that it can be difficult to collect enough samples of blood and tissues to perform quality research.
Picking the right virus candidate for gene therapy
Viruses often get bad press. Likened to Trojan horses they are often associated with disease. But, i t is precisely because of their infectious nature that they can potentially be used as gene vectors - which are vehicles loaded with good copies of malfunctioning genes - and delivered to cells.
Eric Kremer – Delivering therapy beyond the blood-brain barrier
Brain diseases are particularly challenging to treat. Every substance that has to be delivered to the brain needs to overcome several obstacles, such as the blood-brain barrier—a system that prevents potentially dangerous substances, but also many drugs, to enter this organ—,to get to its target.
Peering down protein-DNA interactions to better understand how genes work
Almost every one of our cells has an entire copy of our genome. But only differing subsets of genes are active and expressed in any given cell. Epigenetics is the study of how the activity of our genes is controlled and regulated .
Common links between neurodegenerative diseases identified
Diseases of the central nervous system are a big burden to society . According to estimates, they cost €800 billion per year in Europe. And for most of them, there is no definitive cure.
Cystic Fibrosis: A European Cause
It strikes mainly children and young adults by causing abnormal fluid transport mainly in their lungs, pancreas and intestine. At its most advanced stage, cystic fibrosis still leaves no alternative other than lung transplant.
The Fish that Protects Your Life
More than half of all deaths in Europe are caused by cardiovascular disease, and 80% of all these are due to atherosclerosis.
Stem Cells: A Genetic Perspective
Embryonic or neural stem cells are key tools for future studies on Parkinson’s disease or other degenerative diseases. So far, the only way to obtain embryonic stem cells implied the destruction of an embryo.
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