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Picking the right virus candidate for gene therapy
Picking the right virus candidate for gene therapy
Viruses often get bad press. Likened to Trojan horses they are often associated with disease. But, i t is precisely because of their infectious nature that they can potentially be used as gene vectors - which are vehicles loaded with good copies of malfunctioning genes - and delivered to cells.
New laser to watch DNA-proteins interactions
New laser to watch DNA-proteins interactions
Within the framework of the European ATLAS project, a team of researchers in Naples has created a LASER-based prototype that could revolutionize medicine and our knowledge of the human genome .
Peering down protein-DNA interactions to better understand how genes work
Peering down protein-DNA interactions to better understand how genes work
Almost every one of our cells has an entire copy of our genome. But only differing subsets of genes are active and expressed in any given cell. Epigenetics is the study of how the activity of our genes is controlled and regulated .
Lucia Altucci – Cancer research could benefit from ultra-fast lasers technology
Lucia Altucci – Cancer research could benefit from ultra-fast lasers technology
Cancer research could soon benefit from a new technology allowing investigation of how the DNA interacts with the proteins. Recent advances in tackling the disease stem from a change in our view of the genome —all the genes contained in our DNA.
Common links between neurodegenerative diseases identified
Common links between neurodegenerative diseases identified
Diseases of the central nervous system are a big burden to society . According to estimates, they cost €800 billion per year in Europe. And for most of them, there is no definitive cure.
Monica Di Luca – Parkinson’s treatment revisited to avoid adverse effects
Monica Di Luca – Parkinson’s treatment revisited to avoid adverse effects
According to estimates, more than 1.2 million people in Europe are affected by Parkinson’s disease. Health costs for the disease amount to €11 billion euros per year.
New therapy against rare gene defects
New therapy against rare gene defects
European scientists set up new therapeutic approaches to tackle specific Lysosomal Storage Disorders: a new drug combination and enzyme replacement therapy against Pompe disease and gene therapy against MPS V I (Mucopolysaccharidosis VI).
Two approaches to treat Lysosomal Storage Diseases
Two approaches to treat Lysosomal Storage Diseases
Lysosomes are membrane-bound organelles found in most animal cells. They are responsible for treating cellular waste. Genetic mutations in lysosomal enzymes lead to lysosome malfunction and waste accumulation.
Generoso Andria – Enzyme and gene therapy for treating genetic disorders
Generoso Andria – Enzyme and gene therapy for treating genetic disorders
Lysosomes are intracellular organelles that degrade and recycle ‘waste’ molecules. Lysosomal Storage Disorders (LSDs) comprise a large group of congenital metabolic diseases affecting altogether one in 8,000 newborns.
Advances in Treating Huntington’s Disease
Advances in Treating Huntington’s Disease
Juliet Ross is suffering from Huntington’s Disease, a rare neurological disorder that affects one in 10.000 people. Due to a genetic defect, her body produces a toxic protein that damages neurons in her brain .
Huntington's disease: A treatment in sight?
Huntington's disease: A treatment in sight?
A treatment to directly fight Huntington’s disease could finally be in sight . Until now, therapies for this severely debilitating genetic disorder have only focused on alleviating physical and psychiatric symptoms.
Preventing antibiotic resistance in hospital textiles
Preventing antibiotic resistance in hospital textiles
“Antibiotic resistance threatens a return to the pre-antibiotic era”. The World Health Organisation uses this strong expression when referring to a phenomenon that is rapidly spreading: the increasing resistance of microorganisms to antimicrobial medicines, such as antibiotics .
Wooden Bones
Wooden Bones
Rebuilding bones out of wood, or cartilage out of algae and chitosan is the most spectacular aspect of this particular bioinspiration field.
The Magic Touch
The Magic Touch
The “ nano wrap ” that is being developed to be fitted around an amputee’s upper arm nerve bundle is the ambitious other part of the Smarthand’s robotic hand project.
The Fish that Protects Your Life
The Fish that Protects Your Life
More than half of all deaths in Europe are caused by cardiovascular disease, and 80% of all these are due to atherosclerosis.
Stem Cells: A Genetic Perspective
Stem Cells: A Genetic Perspective
Embryonic or neural stem cells are key tools for future studies on Parkinson’s disease or other degenerative diseases. So far, the only way to obtain embryonic stem cells implied the destruction of an embryo.
Calculating Fertility
Calculating Fertility
We don’t really seem to know all that much about the organ we all come from.
The Secret of Sudden Death
The Secret of Sudden Death
Unlocking the mystery of that 5% of sudden cardiac deaths which are not caused by any apparent anatomic abnormality points to a group of inherited gene mutations in the heart’s ion channels.
Breaking the vicious cycle of antibiotic resistant bacteria
Breaking the vicious cycle of antibiotic resistant bacteria
Bacteria and other microorganisms that cause infections are remarkably resilient and can develop ways to survive drugs meant to kill or weaken them.
Protecting Patient Data
Protecting Patient Data
For every physician and patient, reduction of medical error is a priority issue. 10% of diagnoses and prescriptions are estimated to be flawed.
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