Genetics, Health
Bacterial BioArt
Bacterial BioArt Around 700,000 people are killed by antibiotic resistant infections in the world every year, estimates say. Antimicrobials are increasingly overused and misused, while some organisms are becoming more resistant to antibiotics.
The bacteria talk
The bacteria talk “Let’s start from the end. Our project will not really end in our lifetime”. Puzzling as it may sound, the statement comes from Sarah Goldberg, researcher at the Technion – Israel Institute of Technology in Haifa, one of the leading scientific institutions in Israel.
Digging into the DNA for a successful diet
Digging into the DNA for a successful diet Genes are the latest trend in nutrition, at least going by the burgeoning  legion   of Internet companies offering diets tailored to our genetic make-up.  These services are relatively affordable and simple to use.
Twins help progress and diagnosis of rare Myasthenia
Twins help progress and diagnosis of rare Myasthenia Fourteen pairs of identical twins joined the EU funded medical project “ Fight-MG ”, to fight Myasthenia Gravis . This rare autoimmune disease leads to abnormal fatigability of various skeletal muscles.
Sonia Aknin-Berrih: How rare models suggest new treatment strategies
Sonia Aknin-Berrih: How rare models suggest new treatment strategies Myasthenia Gravis (MG) is a rare auto-immune disease—whereby patients’ immune systems attack their own bodies— arising from a breakdown in communications between the nervous and muscular systems.
Network of experts join forces to fight rare disease
Network of experts join forces to fight rare disease Collaboration between research groups is key in tackling rare diseases such as auto-immune disease Myasthenia Gravis (MG). Indeed, the rarity of the disease means that it can be difficult to collect enough samples of blood and tissues to perform quality research.
Gene correction for a rare disease
Gene correction for a rare disease Angeles suffers from a severe and rare genetic disease called Acute Intermittent Porphyria (AIP). This means, one of her genes restrains her liver to produce a specific protein needed for the metabolism of the blood.
Renewed hope for gene therapy in rare disease
Renewed hope for gene therapy in rare disease Between 30 and 40 million people in Europe suffer from rare diseases —many of them children. As most of these diseases have genetic origins, gene therapy is a major hope for their future cure .
Gloria González-Aseguinolaza - Positive signs for curative treatment against Porphyria
Gloria González-Aseguinolaza - Positive signs for curative treatment against Porphyria Patients with Acute Intermittent Porphyria (AIP) are permanently tired. They continuously suffer acute pain, severe motor affection and an array of neurological problems. AIP affects one in 10,000 people in the EU.
Secrets of youth, based on prevention
Secrets of youth, based on prevention We age in two ways. There is the ageing we count by clock and calendar. And then there is biological ageing. The latter is written into our genes. But, it is also influenced by our lifestyle and history.
Ana Valdes – Twins studies to identify the molecular cause of ageing
Ana Valdes – Twins studies to identify the molecular cause of ageing What makes us age biologically? We have always been intrigued by this question. Yet, it remains a fundamental research challenge.  Now, the EU-funded project, EurHEALTHAgeing , aims to draw together studies of early development with those on longevity and ageing.
Picking the right virus candidate for gene therapy
Picking the right virus candidate for gene therapy Viruses often get bad press. Likened to Trojan horses they are often associated with disease. But, i t is precisely because of their infectious nature that they can potentially be used as gene vectors - which are vehicles loaded with good copies of malfunctioning genes - and delivered to cells.
Eric Kremer – Delivering therapy beyond the blood-brain barrier
Eric Kremer – Delivering therapy beyond the blood-brain barrier Brain diseases are particularly challenging to treat. Every substance that has to be delivered to the brain needs to overcome several obstacles, such as the blood-brain barrier—a system that prevents potentially dangerous substances, but also many drugs, to enter this organ—,to get to its target.
Human Bones from the Lab
Human Bones from the Lab Scientists in Würzburg, in Germany, have created living bone material from human stem cells in their laboratory. The discipline is called tissue engineering and the aim of the scientists is to produce the perfect substitute for bone transplantation.
Healing bone defects using regenerative medicine
Healing bone defects using regenerative medicine Bone is one of the most frequently transplanted tissues. And the demand is rising. Transplants treat large defects like those caused by trauma, complicated fractures, tumour resection or osteoporosis. ...
Heike Walles – A diverse toolbox for regenerating bones
Heike Walles – A diverse toolbox for regenerating bones Bone grafts are among the most sought after tissue transplants in clinical practice. And this demand is expected to rise due to an ageing population.
Physical work, not the main cause of intervertebral disc degeneration
Physical work, not the main cause of intervertebral disc degeneration Even if you do not suffer from pain in the intervertebral discs in your lower back, it is a sure bet that you know someone who does. Yet, surprisingly little is known about what causes this disc degeneration .
Proteins: The Key for all Diseases?
Proteins: The Key for all Diseases? The impact if this challenge could be huge, as this set of data could l ead to new therapies and diagnosing tools for virtually all diseases , including diabetes or cancer.  Proteins are everywhere.
Mapping proteins in space and time within cells
Mapping proteins in space and time within cells The human genome and those of several other organisms have been mapped. But it is proteins that perform the majority of biological functions within every organism .
Ruedi Aebersold – Unravelling the structure and dynamics of large protein complexes
Ruedi Aebersold – Unravelling the structure and dynamics of large protein complexes More than ten years ago, scientists completely mapped the human genome. Now, the attention has turned to enumerating the entire human protein set. Proteins are of interest because they carry out most chemical activities in a cell.
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