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Genetics, Medicine, Health
Peering down protein-DNA interactions to better understand how genes work
Peering down protein-DNA interactions to better understand how genes work
Almost every one of our cells has an entire copy of our genome. But only differing subsets of genes are active and expressed in any given cell. Epigenetics is the study of how the activity of our genes is controlled and regulated .
Lucia Altucci – Cancer research could benefit from ultra-fast lasers technology
Lucia Altucci – Cancer research could benefit from ultra-fast lasers technology
Cancer research could soon benefit from a new technology allowing investigation of how the DNA interacts with the proteins. Recent advances in tackling the disease stem from a change in our view of the genome —all the genes contained in our DNA.
Parasite surveillance to support policy against drug resistance
Parasite surveillance to support policy against drug resistance
Leishmaniasis is a tropical disease known in Europe because it affects dogs. It is caused by the Leishmania parasite carried by sandflies . However, several types of the parasite also affect humans in several regions in the world.
Jean-Claude Dujardin – Overcoming Leishmania’s drug-resistant Trojan horse effect
Jean-Claude Dujardin – Overcoming Leishmania’s drug-resistant Trojan horse effect
Visceral leishmaniasis, or Kala-Azar, is a tropical disease caused by several types of Leishmania parasites transmitted by sandflies.
Common links between neurodegenerative diseases identified
Common links between neurodegenerative diseases identified
Diseases of the central nervous system are a big burden to society . According to estimates, they cost €800 billion per year in Europe. And for most of them, there is no definitive cure.
Monica Di Luca – Parkinson’s treatment revisited to avoid adverse effects
Monica Di Luca – Parkinson’s treatment revisited to avoid adverse effects
According to estimates, more than 1.2 million people in Europe are affected by Parkinson’s disease. Health costs for the disease amount to €11 billion euros per year.
New therapy against rare gene defects
New therapy against rare gene defects
European scientists set up new therapeutic approaches to tackle specific Lysosomal Storage Disorders: a new drug combination and enzyme replacement therapy against Pompe disease and gene therapy against MPS V I (Mucopolysaccharidosis VI).
Two approaches to treat Lysosomal Storage Diseases
Two approaches to treat Lysosomal Storage Diseases
Lysosomes are membrane-bound organelles found in most animal cells. They are responsible for treating cellular waste. Genetic mutations in lysosomal enzymes lead to lysosome malfunction and waste accumulation.
Generoso Andria – Enzyme and gene therapy for treating genetic disorders
Generoso Andria – Enzyme and gene therapy for treating genetic disorders
Lysosomes are intracellular organelles that degrade and recycle ‘waste’ molecules. Lysosomal Storage Disorders (LSDs) comprise a large group of congenital metabolic diseases affecting altogether one in 8,000 newborns.
How many pills? Ask your genes
How many pills? Ask your genes
European researchers have looked how the analysis of your genes could help to determine the dosage for patients who need to take blood thinners.
Anke-Hilse Maitland van der Zee - Blood thinners at the right dose
Anke-Hilse Maitland van der Zee - Blood thinners at the right dose
Coumarins— blood thinners against thrombosis, or blood clotting, are amongst the most widely used drugs worldwide. Millions of mostly elderly people depend on them. But finding the right dosage is a painstaking process.
Better diagnostics for thrombosis are a matter of resources
Better diagnostics for thrombosis are a matter of resources
Cost-effectiveness is paramount for any new medical technology. If pharmaceutical companies do not see a profit, new drugs will never see the light of day.
Advances in Treating Huntington’s Disease
Advances in Treating Huntington’s Disease
Juliet Ross is suffering from Huntington’s Disease, a rare neurological disorder that affects one in 10.000 people. Due to a genetic defect, her body produces a toxic protein that damages neurons in her brain .
Huntington's disease: A treatment in sight?
Huntington's disease: A treatment in sight?
A treatment to directly fight Huntington’s disease could finally be in sight . Until now, therapies for this severely debilitating genetic disorder have only focused on alleviating physical and psychiatric symptoms.
Fighting superbugs
Fighting superbugs
November 18 th is the annual European Antibiotic Awareness Day . Its purpose is to highlight the increase of bacterial resistance to antibiotics on the continent .
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